Process Engineer, Downstream
Job Location:
Frederick, MD - USA
Monthly Salary:
Posted:
Application Deadline:
Vacancies:
Job Summary
Agilent inspires and supports discoveries that advance the quality of life. We provide life science diagnostic and applied market laboratories worldwide with instruments services consumablesapplicationsandexpertise. Agilent enables customers to gain the answers and insights theyseek ---- so they can do what they do best: improve the world around us. Information about Agilent is available at.
Wantto take your knowledge and experience further Ready to provide technical leadership and make key decisions This is your opportunity - not only to join a committed professional and forward-thinking team but also to lead in the design and implementation of complex manufacturing processes and transform broad concepts into structured results-focused projects.
Join a growing team with this exciting new opportunity for an expert levelDownstreamProcess Engineer.Work onadynamic fast-pacedlarge capacity oligonucleotide API production facilitydesign andconstructionproject.Contribute to the growing industry of oligonucleotide (DNA-RNA) based therapeutics.
Responsibilities may include but are not limited to:
Technicalleadfor downstream processes and unit operations.Responsible for process modeling andconsulted on process fit and throughput assessments.
Responsible for process design review for large capital projects includinguserrequirements specifications developmentP&IDs layouts and equipment selection.
Responsible for equipment design and procurement support includingequipment and instrumentation specification/selection equipment procurementFAT/SATinstallation commissioning qualification andturn-overto manufacturing.
Consulted on Automation/Controlsdesign including instrumentationselection equipment interface and equipment module / phase design.
SupportChemical Development inthe developmentcharacterization and scaleupof innovative Oligonucleotide production processes and technologies.
Responsible for Building Information Model (BIM)review forprocess piping and equipmentcleanroom designandgeneralspatial planning to achievemanufacturing requirements.
Responsible forplanningreview and execution ofprocess startup commissioning and qualification activities.
Consultedonproject management aspects including project schedule budget and coordination of multi-disciplinary teams.
Support EHS activities including PHA PSSR and PSM compliance.
REQUIRED:
Bachelors orMasters Degree in Chemical Engineeringor equivalent education/experience.
8 years of combined experience in pharma/biopharma and fine chemicals industryto includeexperience with P&IDs facility layouts mass and energy balances solvent handling equipmentdesign user requirement specifications (URS).
6 years ofexperience with medium tolarge-sized projects through all phases including design design review process hazard analysis equipment procurement installation commissioning and qualification.
DESIRED:
Familiarity with current ASME BPE sanitary piping and equipment design standards electrical standards such as National Fire Protection Association / National Electrical Code (NFPA 70 / NEC) and International Fire and Building Code
Experience with Oligonucleotidemanufacturingdownstreamunit operations and processesincluding:
Column packingpreparativeliquidchromatographybufferpreparationreactionultrafiltration evaporation drying.
Experience with design of industrial control systems including SCADA PLCs and BAS and validation documentation including installation operational and performance qualification (IQ/OQ/PQ) protocols.
Experienceand familiaritywithOSHA Process Safety Management (PSM) program requirements.
Engineering communication and organizational skills to support the safe efficient and compliantdesign construction and startup of an APImanufacturing facility.
Self-motivated hands-on problem solver with the ability to work within multi-disciplinary teams including process development manufacturing validation quality safety and project management personnel.
Additional Details
This job has a full time weekly schedule. Applications for this job will be accepted until at least May 21 2026 or until the job is no longer posted.The full-time equivalent pay range for this position is $124160.00 - $194000.00/yr plus eligibility for bonus stock and benefits. Our pay ranges are determined by role level and location. Within the range individual pay is determined by work location and additional factors including job-related skills experience and relevant education or training. During the hiring process a recruiter can share more about the specific pay range for a preferred location. Pay and benefit information by country are available at: Technologies Inc. is an Equal Employment Opportunity and merit-based employer that values individuals of all backgrounds at all levels. All individuals regardless of personal characteristics are encouraged to apply. All qualified applicants will receive consideration for employment without regard to sex pregnancy race religion or religious creed color gender gender identity gender expression national origin ancestry physical or mental disability medical condition genetic information marital status registered domestic partner status age sexual orientation military or veteran status protected veteran status or any other basis protected by federal state local law ordinance or regulation and will not be discriminated against on these bases. Agilent Technologies Inc. is committed to creating and maintaining an inclusive in the workplace where everyone is welcome and strives to support candidates with disabilities. If you have a disability and need assistance with any part of the application or interview process or have questions about workplace accessibility please email or contact 1-. For more information about equal employment opportunity protections please visit Required: OccasionalRequired Experience:
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