Associate Scientist, Large Molecule

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at .

As guided by Our Credo Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Job Sub Function:

Job Category:

All Job Posting Locations:

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at are searching for the best talent for an Associate Scientist Large Molecule (LM). This role will be within our Drug Product Development & Delivery (DPD&D) Global Process Development (GPD) team and will sit in our Malvern PA location.

Purpose: The candidate for this position will be responsible for process development of fill/finish manufacturing processes of biotherapeutic products. The candidate will support the design and execution of development activities in support of process and fill-finish activities for large molecules (e.g. monoclonal antibodies bi-specifics tri-specifics etc) to ensure the implementation of manufacturing processes that meet all regulatory requirements and expectations.

You will be responsible for:

• Support biologics drug product development activities from discovery through commercialization collaborating with global teams representing functions within the Chemistry and Manufacturing Controls (CMC) at Johnson & Johnsons Innovative Medicine.
• Uses underlying physical chemical and biological principles to identify the mechanisms and kinetics governing process and product performance and scale up and achieve target process performance at all scales.
• Develops fundamental understanding of large molecule parenteral process unit operations on physical/chemical/biological product quality attributes specifically freeze/thaw mixing filtration filling process steps and Process Analytical Technology (PAT) based experiments.
• Develops and uses lab based scale-down models to evaluate process parameters and ranges and builds knowledge of scale up of unit operations to confirm or modify understanding of critical and key parameters.
• Evaluates the suitability of manufacturing processes to existing product process and materials platforms and vice versa.
• Works with other development teams and commercial and clinical supply chain to conduct in depth reviews of process performance data to establish/refine and drive process improvements.
• Opportunity to develop process engineering skills including the use of multi-physics software for process modeling and the statistical analysis of data.

Qualifications / Requirements:

• Bachelors degree in Engineering (Biomedical Bioengineering Chemical Electrical or Mechanical) with 0-3 years experience (including co-op internships or research experience) OR Masters degree with 0-1 year of work experience is required.

• A basic understanding of manufacturing principles and processes preferably with an application to large molecule production.
• Basic understanding and ability to perform data evaluation and statistical analysis.
• Ability to contribute toward and write technical documents as well as the ability to clearly communicate findings and progress to management.
• Ability to collaborate in matrix teams in order to deliver high quality results.
• Motivated self-starter able to work independently with proven problem solving skills.
• Up to 15% international and domestic travel.

#LI-Hybrid

This job posting is anticipated to close on 7/4/2026. The Company may however extend this time-period in which case the posting will remain available on to accept additional applications.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation external applicants please contact us via internal employees contact AskGS to be directed to your accommodation resource.

Required Skills:

Preferred Skills: