Vice President, Biostatistics

• Lead the overall biostatistics strategy across all clinical development programs from early development through registration and post-marketing activities.
• Provide statistical leadership for the design and execution of Phase 3 clinical trials including innovative trial design and methodology (eg adaptive designs and modeling approaches) endpoint selection and sample size determination.
• Oversee the development of statistical analysis plans (SAPs) and contribute to the development of clinical study reports (CSRs) and regulatory submission documents.
• Lead data interpretation and support decision-making at key program milestones including interim analyses and final data readouts.
• Serve as the biostatistics lead in interactions with external data monitoring committees and global health authorities.
• Oversee CROs data vendors and technology platforms to ensure high-quality deliverables on-time execution and compliance with regulatory and industry standards.
• Champion modern data management and statistical computing practices ensuring infrastructure supports scale audit readiness and efficiency.
• Stay abreast of emerging statistical methodologies regulatory trends and industry best practices to ensure the organization remains at the forefront of scientific and statistical innovation.
• Lead and mentor a high-performing biostatistics team including internal staff and external vendors/CRO partners.

Qualifications :

• PhD or masters degree in Biostatistics Statistics or related field.
• 15 years of relevant experience in biotech/pharmaceutical R&D.
• Late stage development particular in Oncology is strongly preferred.
• At least 7 years leading Biostatistics teams including management of statisticians programmers and/or data management groups.
• Demonstrated success in shaping statistical strategy for pivotal trials and regulatory submissions.
• Proven ability to influence senior stakeholders navigate ambiguity and drive alignment across cross-functional teams.
• Strong track record of contributing to late-stage development/regulatory submissions with NDA experience strongly preferred.
• Deep understanding of global regulatory guidelines data requirements clinical operations interfaces and inspection readiness.
• Exceptional communication skills with ability to translate complex statistical concepts into clear actionable insights for diverse audiences.
• Experience managing departmental budgets vendor relationships and technical infrastructure.
• Highly collaborative with strong interpersonal skills and the ability to build trust across teams.
• Strategic thinker with strong scientific rigor and operational pragmatism.
• Thrives in a fast-paced evolving environment; able to manage multiple priorities with clarity and focus.
• Demonstrates integrity accountability and a commitment to continuous learning and team development.
• Comfortable with hands-on leadership in a small-company environment.

Additional Information :

The anticipated base salary for candidates who will work on-site at our San Diego location is between $320000-$350000 per year. The final rate offered to a successful candidate will be dependent on several factors that may include title type and length of experience within the role type and length of experience within the industry education geography and other job-related factors. This position is not eligible for H-1B visa sponsorship.

ORIC Pharmaceuticals Inc. is an equal opportunity employer. ORIC does not discriminate based on race color religion gender sexual orientation gender identity age national origin disability status protected veteran status or any other legally protected characteristics.

Remote Work :

No

Employment Type :

Full-time