Sr. Scientist, Neuroimmunology

Job Description

Location: Boston MA

Position Summary

We are seeking a highly motivated laboratory-based scientist to join the Neuroimmunology team at our Company. This role is ideal for a hands-on experimentalist with expertise in preclinical models neuroimmunology neurodegeneration and translational biology. The successful candidate will independently design and execute in vivo studies generate mechanistic insights into microglial biology and contribute to the discovery of novel therapies for CNS diseases.

Key Responsibilities

• Play a key role in supporting pipeline programs by designing and executing studies interpreting complex datasets and communicating findings to cross-functional teams

• Serve as a hands-on scientist conducting in vivo procedures and downstream analyses.

• Generate and interpret pharmacology efficacy biomarker and mechanistic datasets to support target validation and drug discovery programs.

• Perform CNS immune cell isolation flow cytometry immunophenotyping molecular profiling and histological analyses.

• Collaborate with multidisciplinary teams across pharmacology immunology chemistry biologics biomarker sciences and data science.

• The individual is expected to provide scientific leadership contribute to program strategy and influence decision-making through data-driven recommendations.

Required Qualifications

Education and experience:

• PhD in Neuroscience Immunology Cell Biology Pharmacology Bioengineering Neurology or a related STEM field; postdoctoral industry experience preferred.

OR

Masters degree in Neuroscience Immunology Cell Biology Pharmacology Bioengineering Neurology or a related STEM field with:

• Minimum 6 years of pharmaceutical or biotechnology industry experience.

Required Skills:

• Extensive hands-on experience with rodent in vivo studies

• Experience with mouse models of neurodegeneration neuroinflammation or CNS disease.

• Expertise in flow cytometry CNS immune cell isolation immunohistochemistry and molecular biology techniques.

• Familiarity with omics approaches (RNA-seq single-cell technologies) and data analysis.

• Strong experimental design statistical analysis and problem-solving skills.

• Excellent communication and collaboration skills in a cross-functional research environment.

Preferred Qualifications

• Industry experience supporting discovery or early development programs in CNS disorders.

• Experience with Alzheimers disease Parkinsons disease ALS multiple sclerosis or related neurodegenerative diseases.

• Hands-on experience with transgenic rodent models including behavioral pharmacology and biomarker studies.

• Experience with primary microglia cultures macrophages immune cell assays or iPSC-derived CNS cell systems.

• Familiarity with translational biomarkers PK/PD relationships and mechanism-based drug development.

• Experience working within multidisciplinary drug discovery teams and advancing programs from target validation through candidate selection.

• Prior experience leading collaborative projects in particular the ability to coordinate activities across multiple functions will be an important consideration

The ideal candidate is a highly independent scientist who enjoys working at the bench excels in in vivo experimentation and is passionate about advancing innovative therapies for neurodegenerative diseases.

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The salary range for this role is

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employees position within the salary range will be based on several factors including but not limited to relevant education qualifications certifications experience skills geographic location government requirements and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive if applicable.

We offer a comprehensive package of benefits. Available benefits include medical dental vision healthcare and other insurance benefits (for employee and family) retirement benefits including 401(k) paid holidays vacation and compassionate and sick days. More information about benefits is available at can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:We will consider for employment all qualified applicants including those with criminal histories in a manner consistent with the requirements of applicable state and local laws including the City of Los Angeles Fair Chance Initiative for Hiring Ordinance

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