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Sr Scientist – Biomarker Method Development
Job Location:
Job Location:
Kansas City, KS - USA
Monthly Salary:
Not provided by the employer
Monthly Salary:
Posted:
29 September 2026 (2 days ago)
Posted:
Application Deadline:
29 December 2026
Application Deadline:
Vacancies:
1 Vacancy
Vacancies:
Job Summary
Performing critical work that impacts our industry and our worlds health while problem solving and innovating in the field that is what Sr. Scientists at KCAS Bio get to do every day. If that gets you excited too then maybe working as a Sr. Scientist at KCAS Bio is the role for you.
When you work as a Sr. Scientist in the BioPharma Sciences group at KCAS you get to further our mission by leveraging your knowledge in bioanalytical and scientific principles with a primary focus on biomarker method development. You will design develop optimize and troubleshoot complex bioanalytical methods while utilizing your strong base in scientific principles and theories to assess assay performance data integrity and scientific outcomes.
Our BioPharma Sciences team uses ligand binding assay (LBA) platforms to conduct bioanalytical testing in support of drug discovery preclinical and clinical studies including the quantification of proteins biomarkers and anti-drug antibodies in biological matrices using technologies such as ELISA MSD and other immunoassay-based methods.
In this role we will rely on you to:
- Lead the design development optimization and troubleshooting of ligand binding assays with a primary focus on biomarker method development
- Design experiments and independently evaluate assay performance to establish robust and scientifically appropriate methods
- Develop and optimize assay conditions reagents controls and workflows to address complex biomarker method development challenges
- Apply strong scientific judgment to evaluate assay performance characteristics including precision accuracy sensitivity selectivity specificity and robustness
- Troubleshoot complex assay performance issues identify root causes and develop scientifically sound solutions
- Support method qualification validation and transfer activities as appropriate for the intended use of the assay
- Contribute scientific expertise to PK and immunogenicity/ADA method development activities as applicable
- Act as a technical expert and scientific resource for biomarker assay development performance troubleshooting and problem solving
- Act as lead scientist help design experiments and provide work instructions and technical training to more junior scientific staff
- Review and interpret scientific data and communicate findings recommendations and potential risks to internal teams and clients
- Partner with clients and internal stakeholders to understand scientific objectives and translate those needs into appropriate bioanalytical strategies
- Prepare and review study documentation data summaries protocols and reports as appropriate
- Work collaboratively with Quality Assurance and scientific teams to ensure activities are conducted in accordance with applicable protocols SOPs regulatory requirements and quality standards
- Maintain knowledge of current scientific technological and regulatory developments relevant to biomarkers and ligand binding assay development
- Be responsible for timeline adherence and communication of status to management as required
- Perform all aspects of the job in a way that supports company brand and supports company mission vision and values
To qualify specifically for this role you will have:
- Bachelors Masters or PhD in Biology Biochemistry Immunology or related scientific field with at least 5 years of experience in a bioanalytical laboratory environment
- Demonstrated depth of experience in biomarker method development including the development optimization and troubleshooting of biomarker assays
- Strong hands-on experience with ligand binding assays (LBA) including ELISA MSD or similar immunoassay platforms
- Demonstrated ability to independently design experiments evaluate assay performance troubleshoot complex technical challenges and optimize assay conditions
- Strong understanding of assay performance characteristics including precision accuracy sensitivity selectivity specificity and robustness
- Experience with method development qualification and/or validation in a regulated bioanalytical pharmaceutical biotechnology or CRO environment
- Strong scientific judgment and the ability to interpret complex data and make recommendations based on experimental outcomes
- Experience working within established regulatory and quality frameworks applicable to bioanalytical method development
- Strong written and verbal communication skills with the ability to communicate complex scientific information to internal and external stakeholders
- Ability to provide technical guidance training and mentorship to less experienced scientific staff
Preferred Qualifications:
- Experience developing PK ligand binding assays
- Experience developing immunogenicity/anti-drug antibody (ADA) assays
- Experience working in a GLP-regulated bioanalytical laboratory environment
- Experience interacting with Quality Assurance and supporting regulated studies audits or inspections
- Experience in a CRO environment
- Prior experience serving as a technical lead or scientific lead for assay development programs
(Please note this is a representative summary of responsibilities not a comprehensive or exclusive list of the duties to be performed in any position. Employees must follow instructions and perform additional duties as requested.)
WHO YOU ARE
You will thrive at KCAS Bio if you enjoy a relational environment are purpose- and values-driven embrace constant development and supportive leadership and enjoy being part of innovative work.
WHAT YOULL GET
Our benefits include and extend beyond the traditional package. At KCAS Bio you will enjoy company sponsored events like food trucks family days and spirit will grow in your career with KCAS will be able to connect with like-minded employees to further KCAS Bios approach to key areas such as wellness inclusion and community will engage as an owner in our stock ownership program. You will have access to the latest technology. And you will be able to invest in the community with paid time off to volunteer.
Learn more about the Benefits at KCAS Bio
WHO WE ARE
We are a fast-growing contract research organization (CRO) headquartered in Kansas City pioneering the latest drug development in both human and animal health for our expertise is growing and so is our need for great people to work in nimble empowered teams committed to one anothers growth. At KCAS Bio we advance both great science AND great people.
KCAS Bio is proud to be an Equal Opportunity Employer. Among other things we provide equal employment opportunities without regard to race color religion national origin ancestry marital status veteran status age disability pregnancy genetic information sex sexual orientation gender identity or any other legally protected category; we recruit qualified candidates without regard to citizenship status based on internal processes that enable us to hire the right candidates consistent with the appropriate U.S. Immigration framework; and (3) we work with and provide reasonable accommodations to individuals with disabilities and for sincerely held religious beliefs observances and practices. Anyone who needs reasonable accommodation may send an email to emailprotectedor call (for TTY assistance call 711) and ask for Human Resources.
IND123
We may use artificial intelligence (AI) tools to support parts of the hiring process such as reviewing applications analyzing resumes or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed please contact us.
Required Experience:
Senior IC
About Company
As a full-service bioanalytical CRO and biomarker partner, KCAS Bio helps accelerate drug development in the pharma and biopharma industries with large and small molecule bioanalysis.
