Sr Engineer Process Development

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Position Summary:

We are looking for driven talented Process Engineers to join the Manufacturing Technology & Transfer team within Global Operations. This position is an integral part of our Reagent Development team and is tasked with developing and deploying oligonucleotide manufacturing processes. The individual will partner closely with development teams Quality Production Supply Chain and other engineering groups to develop and transfer sustainable manufacturing processes.

Responsibilities:

• Execute feasibility and development oligonucleotide builds as necessary to support various projects timelines
• Ideate and create manufacturing processes and define technical requirements for new production equipment
• Author procedures and instructions for new manufacturing processes and train production operators to manufacture product in a GMP environment
• Troubleshoot new product and manufacturing process issues related to yield quality and throughput
• Construct and execute controlled experiments including DOEs to optimize processes and scale; address yield/quality issues and drive implementation of solutions into a production environment to meet project goals
• Analyze process test results author reports and inform technical recommendations to improve product and process quality
• Work cross functionally with Product Development Supply Chain Manufacturing Quality EHS and Facilities teams by representing Oligo MTT on NPI core teams
• Ensure successful transfer of knowledge into manufacturing and the sustaining support teams

Requirements:

• Expertise with all oligonucleotide processes (synthesis cleavage/deprotection purification desalting and in-process and final QC) and equipment (synthesizers preparative HPLCs analytical HPLCs MSs UV Specs etc)
• Experience with liquid handlers and ERP systems is a plus
• Demonstrated ability to accomplish goals while working across departments
• Effective communication (both verbal and written) and organizational skills to manage competing project priorities
• Expertise with Statistics Statistical Process Control and DOE techniques
• Experience with cGMP and 21 CFR part 11 and supporting manufacturing in an FDA regulated environment is preferred
• Experience with high volume production in a high tech consumables industry is a plus
• Experience with product development processes and project management is a plus

Education / Experience:

• Typically requires a minimum of 5 years of related oligonucleotide experience with a Bachelors degree; or 3 years and a Masters degree; or a PhD without experience in Chemistry Biochemistry Chemical Engineering or equivalent

Listed responsibilities are an essential but not exhaustive list of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs.

The estimated base salary range for the Sr Engineer - Process Development role based in the United States of America is: $98400 - $147600. Should the level or location of the role change during the hiring process the applicable base pay range may be updated accordingly. The range reflects longterm growth in the role; therefore most candidates are hired between the minimum and middle of the range. Placement depends on experience skills location and internal equity. Additionally all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work including access to genomics sequencing family planning health/dental/vision retirement benefits and paid time off.

We are a company deeply rooted in belonging promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation Illumina has always prioritized openness collaboration and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay regardless of gender ethnicity or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences increase cultural awareness and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex race creed color gender religion marital status domestic partner status age national origin or ancestry physical or mental disability medical condition sexual orientation pregnancy military or veteran status citizenship status and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local state and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local state and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process please contact To learn more visit: The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.