Senior Scientist, Peptide Display Technologies

Job Description Summary

We are seeking a highly motivated Senior Scientist to join the Exploratory Chemical Biology team within the Novartis Biomedical Research in San Diego. The successful candidate will contribute to the discovery of LMW peptide and protein therapeutics through the application of modern display technologies and molecular engineering approaches.

This position provides a unique opportunity to work at the interface of chemical biology protein engineering and emerging therapeutic modalities. The successful candidate will support discovery programs through the design and execution of display selections library constructions molecular characterizations and data analyses in a highly collaborative research environment.

Job Description

Internal Job Title:Senior Scientist I/II

Position Location: onsite San Diego CA

Bring your expertise in display technologies and molecular engineering to one of the industrys most innovative research organizations. As a Senior Scientist in Exploratory Chemical Biology at Novartis Biomedical Research you will help unlock new therapeutic possibilities across small molecules peptides and proteins. Youll collaborate with world-class scientists apply emerging discovery technologies and contribute to building next-generation platforms that enable breakthrough medicines. If you thrive in a fast-paced highly collaborative environment and are excited by scientific innovation this role offers an exceptional opportunity to make a meaningful impact on how future medicines are discovered.

Key Responsibilities:

• Design and execute peptide and protein discovery campaigns using phage mRNA yeast and other display or selection platforms.

• Generate characterize and quality-control combinatorial libraries using cloning PCR DNA assembly mutagenesis and sequencing.

• Identify and optimize discovery candidates through iterative selection molecular engineering and biochemical or biophysical characterization using ELISA flow cytometry BLI SPR and related technologies.

• Analyze data and clearly communicate findings to project teams.

• Implement new technologies workflows and automation approaches to improve discovery efficiency.

Essential Requirements:

• BS MS or recent PhD (within last 2 years) in Molecular Biology Biochemistry Biotechnology Chemical Biology Bioengineering or a related field with 4 years of relevant experience or training. Drug discovery experience preferred.

• Hands-on experience with display technologies (phage yeast and/or mRNA) screening and assay technologies and molecular biology methods including library construction and quality control PCR cloning electroporation and DNA assembly.

• Strong laboratory skills attention to experimental detail and accurate timely documentation in electronic laboratory notebooks.

• Strong organizational and prioritization skills with the ability to manage multiple tasks and deliver results within established timelines.

• Excellent written and verbal communication and interpersonal skills with a demonstrated ability to work effectively in a diverse collaborative team.

Compensation and Benefits:

The salary for this position is expected to range between $93800 and $174200 annually for Senior Scientist I and $98700 and $183300 USD annually for Senior Scientist II. The final salary offered is determined based on factors like but not limited to relevant skills andexperience and upon joining Novartis will be reviewed periodically. Novartis may change the publishedsalary range based on company and market factors.

Your compensation will include a performance-based cash incentive and depending on the level of therole eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health life anddisability benefits a 401(k) with company contribution and match and a variety of other benefits. Inaddition employees are eligible for a generous time off package including vacation personal daysholidays and other leaves.

To learn more about the culture rewards and benefits we offer our people click here.

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment hiring training promotion or other employment practices for reasons of race color religion sex national origin age sexual orientation gender identity or expression marital or veteran status disability or any other legally protected status.

Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If because of a medical condition or disability you need a reasonable accommodation for any part of the application process or to perform the essential functions of a position please send an e-mail to or call 1 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Salary Range

$93800.00 - $174200.00

Skills Desired

Analytical Thinking Chemical Biology Chemistry Clinical Research Clinical Trials Collaboration Curious Mindset Data Analysis Detail-Oriented Ethics Gene Therapy Immunology Machine Learning (ML) Mammalian Cell Culture Medical Research Molecular Biology Patient Care Science