Senior Scientist I Immunohistochemistry
Worcester, MA - USA
Job Summary
Are you an experienced and motivated immunohistochemistry scientist looking to contribute to innovative drug discovery programs in a highly collaborative and dynamic environment Join our Pathology team and help advance research that informs target validation target distribution animal model development pharmacology and combination therapy strategies.
The Pathology team is seeking an immunohistochemistry scientist to perform single-plex and multiplex immunohistochemistry and immunofluorescence assays using advanced multiplex immunofluorescence (mIF) platforms. The successful candidate will work closely with study pathologists project teams histotechnologists and fellow scientists to develop robust assays and generate high-quality quantitative data that support critical research decisions.
This role requires strong technical expertise attention to detail independent judgment and the ability to manage multiple priorities in a fast-paced team-oriented environment.
Key Responsibilities:
- Independently design and execute single-plex and multiplex immunohistochemistry and immunofluorescence assays ensure assay execution meets established quality and performance criteria
- Partner with pathologists and project teams to determine the most appropriate assay design and experimental approach for key project questions including questions related to target validation and expression aligned with project objectives and timelines
- Develop optimize and troubleshoot assays using the Opal and Leica Bond Rx platforms with minimal input from pathologists
- Analyze results and present clear well-organized findings with representative images and quantitative data
- Provide technical leadership in IHC panel design assay optimization and complex assay development
- Apply a thorough understanding of image analysis to support the complete assay-development process from assay design through endpoint generation
- Mentor junior scientists and promote consistent high-quality laboratory practices
- Evaluate emerging technologies and communicate relevant opportunities to the team
- Use Sample Manager DreamPath and other laboratory systems to document and track activities
- Maintain accurate timely and compliant experimental records
Qualifications :
- Bachelors degree in biology/chemistry or related field with 10 years of experience or masters degree with 8 years of experience
- Bachelors or masters degree in biology pathology life sciences or a related discipline with relevant industry experience
- Demonstrated experience performing immunohistochemistry and immunofluorescence assays
- Thorough knowledge of the Opal mIF platform including assay development optimization and troubleshooting
- Experience with image analysis and the ability to understand how image-analysis methods affect assay quality and quantitative endpoints
- Ability to work independently prioritize workload and manage multiple projects and deadlines
- Strong attention to detail and commitment to generating accurate reproducible and well-documented results
- Excellent communication and collaboration skills including the ability to present technical findings clearly to cross-functional project teams
- Microsoft office skills
Preferred Qualifications:
- Qualification in IHC (QIHC)
- Experience with the COMET multiplex immunofluorescence platform
- Knowledge of spatial biology quantitative pathology or image-analysis software
- Familiarity with Sample Manager DreamPath or comparable laboratory tracking systems
- Experience mentoring junior scientists or providing technical guidance to colleagues
- This is an exciting opportunity to join a motivated and collaborative team of immunohistochemistry scientists and histotechnologists. If you enjoy solving technical challenges applying emerging technologies and working with multidisciplinary teams to advance drug discovery we encourage you to consider joining us.
Other Desirable Attributes:
- Well organized
- Attention to detail
- Adherence to established protocols and laboratory documentation requirements
- Ability to work and effectively communicate within a team environment
- Ability to handle multiple projects simultaneously
- Delivery of high-quality timely results
- Excellent oral and written communication skills
- Enthusiastic
- Independent analytical innovative thinker
- Proficiency with MS office-Excel OneNote
Significant Work Activities and Conditions:
- Continuous standing for prolonged periods (more than 2 consecutive hours in an 8-hour day)
- Routine work with chemicals
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:
No
Employment Type :
Full-time
About Company
AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuro ... View more