Senior Scientist (Analytical Development, Cell Therapy)

SeniorScientist (Analytical Development Cell Therapy)

Summary of the group

Join our Cell Therapy Analytical Development team where we develop and deliver robust technologically advanced biological assays to progress cell therapy products from research to commercial stages. Our team supports the end-to-end biological and bioanalyticalcharacterization ofviral vectorandcell therapy products enablingmanufacturing processes formulation drug product development and regulatory filings from IND to BLA and beyond. We collaborate closely with analytical quality and several cross-functional teams including clinical regulatory QA and manufacturing.

Accountabilities

• Develop robustfunctional characterization and molecular analytical methods including method qualification and transfer.

• Make detailed observations analyze data interpret results and exerciseappropriate technicaldiscretion in the design execution and interpretation of experiments independently.

• Carry outanalytical development/sample testing to enablelentiviral vectorupstream and downstream processdevelopment.

• Author/reviewtechnical reports protocols and technical summaries for presentation.

• Present and discuss experimental results at group/project team meetings.

• Workin a team-based structure and interface with research and process development departments.

Essential Skills/Experience

• Bachelors degree in Immunology Cell Biology Biological Sciences Biotechnology or related field with8years of relevant experience or a Masters degree in Immunology Cell Biology Biological Sciences Biotechnology or related field with5 years of relevant experienceoraPh.D. in Immunology Cell Biology Biological Sciences Biotechnology or related field with1 years of relevant experience.

• Biotechnology or pharmaceutical industry experience working withanalyticalforlentiviral vectorand CAR T cellsis.

• Experiencemethod qualification/validationandtech transfer ofcell and gene therapy analytical methods isa.

• Highly proficientinimmunology techniques is such asELISA or similar technology platforms.

• Highly proficientinmolecular biologytechniques is such asqPCRdPCRfor gene edit evaluationon target/off target analysis.

• Exhibit excellent written and oral communication skills.

• Good timemanagement and organizational skills with the ability to prioritize tasks from multiple projects to meet timelines.

Desirable Skills/Experience

• Experience inbiophysicalanalysissuch as DLS HPLCmassspectrometry and capillary electrophoresis Flowvirometryis a plusfor lentiviral vectorcharacterization isa plus.

• Experience withNGS is a plus

When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work atpaceand challenge perceptions.Thatswhy we work on average a minimum of three days per week from the office. But thatdoesntmeanwerenot flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca we are driven by our commitment to deliver accelerated growth and make peoples lives better. Our inclusive network of diverse and high-performing teams supports each other with trust and respect. We thrive on curiosity and problem-solving constantly learning and evolving. With opportunities for global careers and great rewards AstraZeneca is where you can make a real impact.Ready to make a difference Apply now to join our team!

The annual base pay for this position ranges from $112304 to $168456. Our positions offer eligibility for various incentivesan opportunity to receive short-term incentive bonuses equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs paid time off (i.e. vacation holiday and leaves) as well as health dental and vision coverage in accordance with the terms of the applicable plans.