Senior Engineer Modeling & Simulation

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer heart disease inflammatory conditions rare diseases and obesity and obesity-related conditions. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Engineer

Lets do this. Lets change the this vital role you will collaborate closely with Design Engineering Quality Systems Engineering Manufacturing Process Development Data Science Regulatory and Digital Technology teams to deliver enterprise-level modeling capabilities for prefilled syringes autoinjectors and other combination products.

• Developvalidate qualify and deploy advanced computational models (InSilico modeling assets) for combination products.

• Applyfirst-principles/analytical modeling numerical methodsfinite element analysis (FEA)surrogate modelingandAI/ML techniquessolvecomplex mechanical structural fluidic thermal and multi-physics problems.

• Develop digital models that improve understanding of device performance design robustness failure mechanisms and system behavior throughout the product lifecycle.

• Build computational models supporting design verification and validation design space developmentmanufacturing robustnessroot cause investigations complaint investigations lifecycle management new product development and feasibility assessments.

• Identifymodeling assumptions requirements specifications and acceptance criteriaappropriate forInSilico evaluation of combination products.

• Analyze simulation results and communicate engineering insights to support technical decision making specification development and risk reduction.

• Explore novel computational approaches automation strategies AI-enabled engineering methods and data-driven modeling techniques.

• Develop proof-of-concept modeling solutions for emerging engineering challenges and complex product behaviors.

• Collaborate with multidisciplinary teams across Product Development Manufacturing Quality Regulatory Data Science and Systems Engineering.

• Contribute to project planning backlog prioritization Agile/Scrum activities and continuous improvement initiatives.

• Communicate complex technical concepts through clear reports presentations and engineering documentation.

• Promote modeling and simulation best practices across the organization.

We are all different yet we all use our unique contributions to serve patients. The professional we seek is a leader with these qualifications.

Basic Qualifications:

Doctorate degree in Mechanical Engineering Biomedical Engineering or Civil Engineering(related to computational modeling and simulation).
OR
Masters degree in Mechanical engineering Biomedical Engineering or Civil Engineering and 2 years of relevant experience in computational modeling and simulation.
OR
Bachelors degree n Mechanical Engineering Biomedical Engineering or Civil Engineering and 4 years of relevant experience in computational modeling and simulation.
OR
Associates degree and 8 years of Engineering Experience (Mechanical Engineering Biomedical Engineering or Civil Engineering)
OR
High school diploma / GED and 10 years ofEngineering Experience (Mechanical Engineering Biomedical Engineering or Civil Engineering)

Preferred Qualifications

• Demonstratedexpertisein physics-based modeling of mechanical systems.

• Programming experience in Python MATLAB or C.

• Finite Element Analysis (FEA) experience with structural contact nonlinear fluidic thermal and multi-physics problems.

• Experience with SIMULIA / 3DEXPERIENCE (preferred) ABAQUS ANSYS LS-DYNA or COMSOL.

• Experience with surrogate modeling reduced-order modeling AI/ML-enabled engineering workflows or data-driven prediction methods.

• Experience with Git or GitLab version control CI/CD workflows and model automation.

• Experience with uncertainty quantification sensitivity analysis Monte Carlo simulationandDesign for Six Sigma (DFSS)methods.

• Knowledge of combination products medical device development design controls V&V and FDA-regulated environments.

• Strong technical documentation presentation and cross-functional communication skills.

• Intellectual curiosity and ability to learn new frameworks algorithms and technologies rapidly.

• Ability to manage multiple priorities and work effectively in a highly collaborative environment.

• Interest inAgenticAI to deploy modeling assets and encourageexploration ofAI-enabled Insights

• Strong analytical and critical thinking skills.

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills experience and qualifications.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts
• A discretionary annual bonus program or for field sales representatives a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

In any materials you submit you may redact or remove age-identifying information such as age date of birth or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.