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Senior Director, Commercialization Strategy & Operations Enablement

Argenx


Job Location:

Boston, NH - USA

Yearly Salary: USD 236000 - 324500
Posted: 29 September 2026 (21 hours ago)
Application Deadline: 27 December 2026
Vacancies: 1 Vacancy

Job Summary

Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back. argenx is preparing for multi-dimensional expansion to reach more patients through a rich pipeline of differentiated assets led by VYVGART our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG and with the potential to treat patients across dozens of severe autoimmune diseases.

We are building a new kind of biotech company one that maintains its roots as a science-based start-up and pushes our commitment to innovate across all corners of our business. We strive to inspire and grow our company our partnerships our science and our people because when we do we deliver more for patients.

argenx is scaling a global commercialization engine to reach more patients across indications and geographies. This role creates leverage for the Chief Commercialization Officer and Commercialization Leadership Team by translating strategy into focus decisions execution and scalable ways of working.

The Senior Director willoperateat the intersection of strategy operations communications and organizational effectiveness. They will help the CCO prioritize the highest-value work leadtheCommercializationleadershipteam (CLT)operatingrhythmconnect cross-functional efforts and advancecritical commercializationd prioritieswhile preserving the empowered entrepreneurial argenx Way.

Location:IdeallyBoston-basedbut can be flexible withEast Coast-based(with the ability to regularly travel to Boston and other key argenxlocations inclusive of Ghent)

Key Responsibilities

Strategic partner to the CCO

  • Serve as a trusted thought partner to the CCO translating strategic priorities into a clear operating agenda.

  • Maintain an integrated view of priorities decisions commitments risks and organizational needs.

  • Anticipate issues surface trade-offs and helpdeterminewhat requires CCO/CLT attention versus local decision-making.

  • Bring structure and sound judgment to ambiguous high-stakes topics.

Lead the CLT operatingrhythm

  • Design and continuously improve the CLT cadence agendas pre-reads decision forums action tracking and follow-through.

  • Ensure leadership time is focused on the most important cross-functional cross-geography and enterprise topics.

  • Partner with topic owners to frame decisions clearly including the recommendation input decision owner and desired outcome.

  • Capture decisions actions owners and timing; ensure accountability through closure.

  • Strengthen alignment and collaboration across Commercialization leaders regions functions and communities.

Drive strategic priorities and execution

  • Build and manage an integrated Commercialization strategic agenda across priorities milestones dependencies decisions and risks.

  • Lead or support high-prioritycommercializationinitiativesfrom problem definition through implementation.

  • Connect work across Commercial Medical Affairs & Evidence Generation Market Access regions/countriesasset/indicationteamsand enterprise partnerssuch asDevelopment.

  • Identifyduplication unclear ownership bottlenecks and misalignmentand help resolve them quickly.

Build scalable digital and AI-enabled ways of working

  • Establish simple effective systems for managing priorities decisions communications and follow-through.

  • Apply digital tools data automation and AI to improve synthesis meeting preparation knowledge flow reporting and organizational learning.

  • Champion adoption of approved digital and AI tools in ways that improve speed clarity quality and productivity whilemaintainingappropriate governance.

  • Build capability in others and reduce reliance on manual leader-dependent processes.

Qualifications

  • Advanced degree (Master or MBA) in business or health-related discipline

  • Significant experiencein strategic operations chief of staff business operations program leadership commercial strategy or top-tier consulting supporting senior executives

  • Proventrack recordleading complex cross-functional strategic projects end-to-end leading without authority in a complex fast-growing network of empoweredteamsorganization.

  • Ideallyat least 5 years of Project Management experience in a Pharmaceutical or Biotech environment.

  • Strong understanding of commercialization in biotechpharma rare disease immunology specialty care or similarly complex healthcare environments - ideally across multiple parts of the value chain (Commercial Medical Affairs R&D).

  • Deep understanding of the US market withat least 10 years of Biopharma commercialization experience preferred.

  • Strong business understandingand prioritization judgment - able to tell what truly needs CCO/CLT attention and what should be decided closer to the work.

  • Excellent written and verbal communication skills including the ability to shape executive-ready narratives pre-reads Board materials and leadership communications.

  • Strong facilitation and meeting-design skills witha track recordof making seniorleaders timemore productive and driving discussions to clear actions.

  • Demonstrated ability to translate strategy into operating rhythm leadership agendas decision forums and follow-through mechanisms.

  • Strong organizational navigation skills with the ability to build trust and influence without relying on hierarchy.

  • Proven ability to manage confidential sensitive and high-stakes information with discretion.

#LI-hybrid

For applicants in the United States: The annual base salary hiring range for this position is $236000.00 - $324500.00 USD. This range reflects our good faith estimate at the time of posting. Individual compensation is determined using objective inclusive and job-related criteria such as relevant experience skills demonstrated competencies and internal equity. This means actual pay may differ from the posted range when justified by these factors. Because market conditions evolve pay ranges are reviewed regularly and may be adjusted to remain aligned with external benchmarks.

This job is eligible to participate in our short-term and long-term incentive programs subject to the terms and conditions of those plans and applicable policies. It also includes a comprehensive benefits package including but not limited to retirement savings plans health benefits and other benefits subject to the terms of the applicable plans and program guidelines.

At argenx all applicants are welcomed in an inclusive environment. They will receive equal consideration for employment without discrimination on the basis of race color religion sex sexual orientation gender identity national origin protected veteran status disability or any other applicable legally protected characteristics. argenx is proud to be an equal opportunity employer.

Before you submit your application CV or any other personal details to us please review our argenx Privacy Notice for Job Applicants to learn more about how argenx B.V. and its affiliates (argenx) will handle and protect your personal data. If you have any questions or you wish to exercise your privacy rights please contact our Global Privacy Office by email at .

If you require reasonable accommodation in completing your application interviewing or otherwise participating in the candidate selection process please contact us at . Only inquiries related to an accommodation request will receive a response.


Required Experience:

Director


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Reaching Patients Through Immunology Innovation

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