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Principal Engineer, Algorithm ECG

Danaher


Job Location:

Irvine, CA - USA

Monthly Salary: Not provided by the employer
Posted: 2 October 2026 (2 days ago)
Application Deadline: 30 December 2026
Vacancies: 1 Vacancy

Job Summary

Bring more to life.

Are you ready to accelerate your potential and make a real difference within life sciences diagnostics and biotechnology

At Masimo one of Danahers 15 operating companies our work saves livesand were all united by a shared commitment to innovate for tangible impact.

Youll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danahers system of continuous improvement you help turn ideas into impact innovating at the speed of life.

Masimo is a global medical technology company that develops and produces a wide array of industry-leading monitoring technologies including non-invasive measurements sensors patient monitors and automation and connectivity solutions. Our mission is Masimo innovations empower clinicians to transform patient care. When you join our team youll be part of a culture thats driven by passion challenging the status quo and making an impact in the lives of others.

Learn about the Danaher Business System which makes everything possible.

The Principal Engineer Algorithm ECG is responsible for the architecture development and advancement of ECG signal processing algorithms that support accurate and reliable cardiac monitoring across Masimos non-invasive platforms. This role provides technical and project leadership for the innovation in ECG-based measurements including heart rate rhythm analysis and advanced cardiac insights translating complex physiological signals into clinically meaningful outputs.


This role collaborates closely with cross-functional teams spanning hardware software systems and clinical disciplines to develop high-performance regulatory-compliant solutions from concept through commercialization.


The position reports to the Manager Algorithm ECG and is part of the R&D Algorithm Engineering department located in Irvine CA and will be an on-site role.


In This Role You Will Have The Opportunity To:


  • Lead the design and development of advanced ECG signal processing algorithms including filtering feature extraction waveform delineation and rhythm classification.
  • Architect scalable algorithm frameworks for ECG analysis supporting real-time embedded implementation and cloud-based analytics where applicable.
  • Develop and optimize algorithms for heart rate detection arrhythmia identification and ECG morphology analysis.
  • Design and conduct validation strategies using clinical datasets to ensure algorithm accuracy robustness and generalizability across diverse patient populations.
  • Translate clinical and regulatory requirements into algorithm design inputs ensuring compliance with applicable standards (e.g. FDA IEC).

The Essential Requirements Of The Job Include:

  • B.S. Degree in Electrical Engineering Biomedical Engineering Computer Engineering or a related field.
  • 12 years of relevant experience in ECG algorithm development signal processing or related domain.
  • Deep expertise in ECG signal processing digital signal processing and statistical modeling.
  • Proven experience developing ECG algorithms including waveform detection and cardiac feature extraction.
  • Strong programming skills in C/C MATLAB Python or similar.
  • Experience working with large-scale physiological or clinical datasets.

It would be a plus if you also possess previous experience in:

  • Masters or Ph.D. in Electrical Engineering Biomedical Engineering Computer Engineering or a related field.
  • Experience with arrhythmia detection/classification algorithms or cardiac monitoring systems.
  • Knowledge of cardiac physiology and electrophysiology principles.
  • Experience applying machine learning techniques to ECG or time-series physiological data.
  • Familiarity with wearable or ambulatory ECG systems and associated signal challenges.

Masimo a Danaher operating company offers a broad array of comprehensive competitive benefit programs that add value to our lives. Whether its a health care program or paid time off our programs contribute to life beyond the job. Check out our benefits at Danaher Benefits Info.


The annual salary rangeORthe hourly range for this role is $170000 - $ is the range that we in good faith believe is the range ofpossible compensationfor this role at the time of this posting. This range may bemodifiedin the future.


This job is also eligible for up to a 15% annual bonus.


We offercomprehensivepackage of benefits including paid time off medical/dental/vision insurance and 401(k) to eligible employees.


Note: No amount of payis considered to bewages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole discretion unless and until paid and may be modified at the Companys sole discretion consistent with the law.

Join our winning team today. Together well accelerate the real-life impact of tomorrows science and technology. We partner with customers across the globe to help them solve their most complex challenges architecting solutions that bring the power of science to life.


For more information visit .


Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race color national origin religion sex age marital status disability veteran status sexual orientation gender identity or other characteristics protected by law.


The U.S. EEO posters are available here.


For candidates who are based outside of New York City or who are applying for roles outside of New York City for more information about conditions of any job offer please click here.


We comply with federal and state disability laws and make reasonable accommodations for applicants and employees with disabilities. If reasonable accommodation is needed to participate in the job application or interview process to perform essential job functions and/or to receive other benefits and privileges of employment please contact:1- or .


Required Experience:

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