Principal Data Scientist

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer heart disease inflammatory conditions rare diseases and obesity and obesity-related conditions. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Principal Data Scientist

What you will do

Lets do this. Lets change the this vital role you will play a key part in designing developing and deploying scalable AI/ML solutions and agentic systems to drive innovation efficiency and regulatory compliance across the organization.

You will collaborate with multi-functional teams including software engineers data engineers business partners and quality professionals to design and implement responsible and ethical AI-driven capabilities that support strategic business objectives.

• Innovation & Research Translation: Stay at the forefront of AI/ML advancementsespecially in the agentic AI and knowledge graph spacesand translate emerging techniques into enterprise-ready applications.
• Agentic System Design & Innovation: Architect and deploy agent-based and multi-agent AI/ML systems to enhance automation decision-making and operational efficiency leveraging modern frameworks and GenAI capabilities.
• Data Excellence & MLOps Governance: Champion robust data science practices and develop scalable auditable MLOps pipelines. Enforce standards for versioning testing monitoring documentation and security to ensure high-quality model lifecycle management.
• Enterprise Integration & Cross-Functional Alignment: Partner with technology product and business team members to align AI initiatives with enterprise goals. Ensure solutions are traceable interoperable and embedded within Amgens digital Quality ecosystem.
• Responsible & Ethical AI: Embed principles of ethical AIincluding fairness transparency privacy and explain-abilityinto the design and deployment of AI/ML solutions. Ensure alignment with Amgens Quality and Compliance standards and global regulatory frameworks.

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The professional we seek is a go getter with these qualifications.

Basic Qualifications:

Doctorate degree and 2 years of Data Science Software/ML Engineering experience
OR
Masters degree and 4 years of Data Science Software/ML Engineering experience
OR
Bachelors degree and 6 years of Data Science Software/ML Engineering experience
OR
Associates degree and 10 years of Data Science Software/ML Engineering experience
OR
High school diploma / GED and 12 years of Data Science Software/ML Engineering experience

Preferred Qualifications:

• Demonstrated success providing technical leadership to teams delivering AI machine learning generative AI analytics or intelligent automation products in production.
• Experience delivering AI-enabled solutions within GxP-regulated biotechnology pharmaceutical healthcare or life-sciences environments.
• Strong understanding of GxP principles data integrity computer-system validation risk-based validation change control and regulated model lifecycle management.
• Proven expertise designing and implementing AI machine learning and generative AI applications including agent-based or multi-agent systems.
• Experience with frameworks and patterns such as LangChain LangGraph LlamaIndex retrieval-augmented generation GraphRAG vector search and knowledge graphs.
• Advanced proficiency in Python and common machine-learning libraries such as PyTorch TensorFlow scikit-learn or equivalent technologies.
• Experience with large language models prompt and context engineering tool calling model evaluation guardrails and human-in-the-loop design.
• Proficiency with data-engineering technologies and methods including SQL Apache Spark data pipelines data modeling and distributed processing.
• Experience developing full-stack applications and integrating AI solutions with enterprise platforms APIs data products and business workflows.
• Strong knowledge of MLOps and LLMOps practices and tools including MLflow CI/CD pipelines automated testing observability model monitoring and infrastructure as code. Experience with cloud and data platforms such as Databricks AWS Microsoft Azure or Google Cloud Platform.
• Demonstrated ability to manage a portfolio of AI opportunities balance experimentation with production delivery and connect technical outcomes to measurable business value.
• Experience developing reusable AI capabilities technical standards enablement materials or communities of practice. Strong problem-solving skills and the ability to operate effectively in complex ambiguous and rapidly evolving environments.
• Excellent written and verbal communication skills with the ability to influence technical business quality and executive stakeholders.
• Demonstrated ability to mentor others lead through influence and build productive relationships across functions and geographies.
• High degree of initiative accountability self-motivation and effectiveness in global cross-functional teams.

What you can expect of us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills experience and qualifications.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts

A discretionary annual bonus program or for field sales representatives a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

In any materials you submit you may redact or remove age-identifying information such as age date of birth or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range