Manager, Applied AI, Advanced Informatics

Build a future together

The Manager Applied AI is a research-facing technical role within the Advanced Informatics team responsible for designing and developing applied AI solutions across health data systems and analytical pipelines. This role works closely with senior applied AI leaders to formulate ML problems against complex health data validate methods against clinical ground truth and build reusable analytical capabilities that the broader informatics team depends on.

The ideal candidate brings solid grounding in AI/ML theory hands-on experience applying it to real-world data problems and is excited to deepen their expertise at the intersection of machine learning and health informatics.

When & where:
This can be a remote position in the US or on-site position at our Tarrytown NY Armonk NY or Warren NJ offices.

Discover your role:

• Design and develop applied AI/ML solutions for health informatics use cases from problem framing and data exploration through model development and evaluation.
• Translate business and clinical informatics challenges into well-scoped AI/ML problem statements with clear success criteria.
• Build and maintain ML pipelines including data ingestion feature engineering model training and evaluation in close collaboration with production engineering.
• Conduct experiments benchmarking and ablation studies to validate model performance and inform modeling decisions.
• Partner with clinical informaticists data engineers and production AI/ML engineers to integrate models into informatics workflows.
• Stay current with advances in foundation models LLMs retrieval-augmented generation and their application to biomedical and health data domains.
• Contribute to research documentation internal technical reports and where appropriate external publications or conference presentations.
• Communicate model behavior limitations and performance clearly to both technical and non-technical stakeholders.

This role requires:

Bachelors degree (BS) in Computer Science Machine Learning Data Science Biomedical Informatics Statistics or a closely related field required. Ph.D. or Masters degree strongly preferred given the research-facing nature of this role.

Minimum Years of Experience: 46 years of progressive experience in applied AI/ML with demonstrated ability to independently develop and evaluate models. Ph.D. graduates with relevant research experience may be considered at the lower end of this range.

Knowledge Skills & Abilities (Required):

• Solid understanding of supervised unsupervised and self-supervised learning; deep neural networks; and modern ML frameworks (PyTorch TensorFlow or equivalent).
• Strong command of Python and the scientific ML stack (scikit-learn HuggingFace Transformers pandas NumPy etc.)
• Experience designing and evaluating NLP or multimodal models including fine-tuning or prompt engineering with large language models.
• Proficiency with experiment tracking model versioning and reproducible research practices (MLflow W&B DVC or similar).
• Familiarity with cloud-based ML infrastructure (AWS SageMaker GCP Vertex AI Azure ML or equivalent).
• Ability to drive technical work independently and communicate findings clearly across teams.

Knowledge Skills & Abilities (Preferred):

• Experience with health or life sciences data EHR/EMR records claims data clinical notes genomic data or imaging.
• Informatics domain knowledge (strong plus): familiarity with medical terminologies and ontologies (SNOMED CT ICD-10/11 LOINC RxNorm OMOP CDM) and machinable health data standards.
• Published work or open-source contributions in applied ML NLP or computational biomedicine.
• Experience with MLOps pipelines CI/CD for ML and model observability in production environments.
• Familiarity with federated learning privacy-preserving ML or working with data use agreements in regulated environments.

Does this sound like you Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race color religion or belief (or lack thereof) sex sexual orientation gender identity or expression gender reassignment marital or civil partnership status civil status pregnancy or parental status age disability nationality citizenship status ethnic or national origin membership of the Traveler community familial status genetic information military or veteran status or any other characteristic protected under applicable law. Where required we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process unless such accommodation would impose undue hardship.

Where necessary we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment specific role level and your skills and some countries collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include depending on country and role: annual bonuses or other incentive plans equity awards pension or retirement benefits 401(k) company match health and wellness programs fitness centers insurance benefits (e.g. medical dental vision life and disability) paid time off and family support benefits. For additional information about Regeneron benefits in the U.S. please visit For other locations additional information will be provided during the recruitment process. If you have any questions please speak with your recruiter.

Please be advised that at Regeneron we believe we do our best work when we are together. For that reason many roles are required to be performed onsite. Please speak with your recruiter and hiring manager for more information about onsite expectations for your role and location.

As part of the recruitment process certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)