Global Director, Forecasting – Infectious Disease
Gaithersburg, MD - USA
Job Summary
Global Director Forecasting Infectious Disease (ID)
Gaithersburg MD
Global Insights Analytics & Forecasting BBU
Hybrid Work - on average 3 days a week from office
The Director is a senior global forecasting leader responsible for demand forecasting across the Infectious Disease portfolio spanning early-stage late-stage and in-market assets as well as business development and investment case building. The role serves as the global forecasting lead and strategic thought partnertoEarly Commercial Finance Market Access & Pricing Marketing Medical Research &Development and Business Development teams. The position also includes vendor and resource management to ensure rigorous use of data and analytics within forecasting continuous improvement of forecasting approaches and delivery of decision-grade commercial assessments. Time allocation may vary by business cycle and portfolio priorities.
Youllplay a critical role in shaping global commercial expectations portfolio choices risk and opportunity framing and executive decision-making for early-stage late-stage in-market and external business development opportunities.
Whatyoulldo
Global Forecasting Leadership (Core Accountability)
Lead global short- and long-term demandforecastsincluding patients volume treatment starts and revenuefor ID assets using robust patient-based and market-based models.
Own forecastmethodology assumptions and governance ensuring objectivity transparency and consistency with enterprise standards.
Develop and refine forecasts for early-stage late-stageassets to support stage-gate decisions portfolio prioritization investment choices and resource allocation.
Use primary market research epidemiology competitive intelligence access and pricing dynamics real-world evidence and other relevant data and analytics to inform forecast assumptions and models.
Proactivelyidentifyand quantify key risks and opportunities through scenario and sensitivity analyses.
Partner closely with Early Commercial Finance Market Access & Pricing Marketing Medical Research &Development Business Development and regional or market teams to ensure alignment on assumptions and implications.
Support global business planning governance reviews portfolio decisions and opportunity assessments with clear executive-ready narratives.
Serve as a trusted advisor to senior global leaders clearly articulating forecast drivers changes uncertainties and strategic implications.
Business Development and Investment Case Building
Lead forecasting and commercial case development for business development opportunities including in-licensing partnerships acquisitions and other external innovation opportunities.
Build patient-based market models revenue forecasts risk-adjusted scenarios and commercial inputs to valuation and investment cases.
Conduct commercial due diligence by assessing unmet need patient pathways market evolution competitive dynamics access and pricing considerations and strategic fit.
Translate incomplete or uncertain evidence into transparent assumptions scenarios trade-offs and recommendations for governance and executive decision-making.
Ensure alignment between business development forecasts internal pipeline forecasts therapeutic area strategy and portfolio planning.
Forecasting Capability and Resource Leadership
Ensure relevant data analytics and insights are applied appropriately to forecasting scenario development and business case building.
Manage and prioritize internal forecasters contractors and external vendors supporting forecasting and business development deliverables.
Partner with data and analytics specialists Global IA&F and GIBEX capability teams to evaluate and deploy data sources tools and modeling approaches that strengthen forecasts.
Identifyopportunities to embed AI and automation into forecasting workflows to improve efficiency scalability transparency and decision quality.
Champion continuous improvement in forecasting processes AI-enabled modeling and automation.
Contribute to the development and sharing of global best practices across the ID forecasting community.
Essential for the role
Bachelors degree ina quantitative scientific health or business-relatedfield such as Statistics Economics Mathematics Engineering Life Sciences or Decision Science.
4 years experience in global pharmaceutical commercial forecasting including early-stage late-stage launch and/or in-market assets.
Experience supporting business development evaluations commercial due diligence opportunity assessments or investment case development.
Hands-on model ownership experience including build refresh and performance tracking across short- and long-term horizons.
Expertise inscenario-based forecasting sensitivity analysis and driver-based narratives to support senior decision-making.
Strong capability using multiple data and evidence sourcessuch as epidemiology claims real-world evidence syndicated data competitive intelligence and primary researchto build coherent decision-grade forecasts.
Demonstrated forecast governance and model risk discipline including traceable assumptions documentation and clear explanations.
Strong understanding of global market access pricing reimbursement policy and regional market dynamics and how they affect demand.
Ability to translate complex forecasts andsupportingevidence into clear executive-ready insights options and recommendations.
Strong commercial and financial acumen across key demand and valuation levers including positioning adoption competition lifecycle events probability of technical and regulatory success and risk adjustment.
Desirable for the role
Advanceddegree such as an MBA MS MPH or PhD in Economics Statistics Decision Sciences Life Sciences or a related field.
Infectious Disease and/or Rare Disease experience including familiarity with immunization dynamics patient-based forecasting and lifecycle management in preventive or infectious disease therapies.
Experience forecasting across multiple geographies and working with global regional and market stakeholders.
Demonstrated ability to work effectively with ambiguity and limited evidence in early-asset and business development settings.
Changeleadership:builds adoption for new tools processes and ways of working across cross-functional stakeholders.
Product perspective forforecasting:defines user needs success measures and a roadmap for global portfolio forecasting capabilities.
Office Working Requirements
When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
The annual base pay for this position ranges from $194571.20 - 291856.80 USD. Our positions offer eligibility for various incentivesan opportunity to receive short-term incentive bonuses equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs paid time off (i.e. vacation holiday and leaves) as well as health dental and vision coverage in accordance with the terms of the applicable plans.
#LI-Hybrid
Date Posted
01-Sept-2026Closing Date
07-Sept-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.
Required Experience:
Director
About Company
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, ... View more