Director, Data Management
Job Location:
San Diego, CA - USA
Yearly Salary:
Posted:
Application Deadline:
Vacancies:
Job Summary
Job Title: Director Data Management
Location: San Diego or Remote U.S.
Job Type: Full-Time
Who We Are
Avenzo Therapeutics Inc. (Avenzo or Company) is a clinical-stage biotechnology company focused on developing next-generation oncology therapies for patients. The Company was co-founded in 2022 by Drs. Athena Countouriotis and Mohammad Hirmand (former CEO and CMO of Turning Point Therapeutics Inc. respectively). Our team is passionate about and committed to advancing a pipeline of potentially differentiated targeted oncology programs that make a difference in the lives of people with cancer. The Company is headquartered in San Diego California.
Position Summary
Reporting to the Senior Director Data Management the Director Data Management will be responsible for performing or overseeing vendors to perform Data Management operational end-to-end activities and participate as an active member in a cross-function study team to plan lead and execute tasks required for assigned clinical studies across all phases. The director will oversee and lead data management project activities coordinate interdepartmental and client communication and help resolve administrative and site issues.
Essential Job Functions and Responsibilities
- Provide leadership and oversight of outsourced Clinical Data Management activities across Avenzos clinical development programs ensuring delivery of high-quality reliable and inspection-ready clinical data
- Serve as a Data Management representative on cross-functional study teams and provide strategic input throughout study planning execution analysis and reporting
- Oversee Data Management CROs and third-party vendors including performance management issue escalation risk mitigation and delivery of study milestones
- Ensure timely execution of database build data review external data reconciliation query management and database lock activities
- Establish and maintain data quality standards oversight plans metrics and processes to ensure data integrity and regulatory compliance across studies
- Identify assess and proactively manage data-related risks that may impact study timelines data quality or regulatory deliverables
- Collaborate closely with Clinical Operations Biostatistics Statistical Programming Clinical Pharmacology Medical Writing Regulatory Affairs and Quality to support development objectives
- Ensure availability of high-quality clinical data to support interim analyses DSMB reviews regulatory submissions and final study reporting
- Lead data review and cleaning strategies and ensure effective oversight of vendor deliverables and issue resolution
- Support inspection readiness activities including maintenance of appropriate documentation vendor oversight records and data management deliverables
- Ensure compliance with ICH-GCP CDISC standards internal SOPs and applicable regulatory requirements
- Oversee the implementation and effective use of EDC and related clinical data systems and support evaluation of new technologies and process improvements
- Drive continuous improvement initiatives to enhance efficiency quality scalability and consistency of Data Management processes.
- Communicate study status key metrics risks and mitigation plans to cross-functional teams governance committees and senior leadership
- Build mentor and develop Data Management staff and contribute to talent acquisition onboarding succession planning and employee development
- Foster a culture of collaboration accountability quality and continuous improvement across the Data Management function
Preferred Qualifications
- Bachelors degree in life sciences data science computer science or related field required with 10 years of progressive clinical data management experience in the life sciences industry or an equivalent combination of academic and industry experience
- Proven experience leading outsourced Clinical Data Management activities and providing strategic oversight of CROs and third-party vendors across multiple clinical programs
- Demonstrated success managing complex global clinical trials and partnering effectively with cross-functional stakeholders in a matrixed environment
- Experience building leading mentoring and developing high-performing Data Management teams; prior people management experience preferred
- Strong understanding of clinical development processes with experience supporting Phase I through Phase III clinical trials and global development programs
- Deep expertise in vendor governance performance management and risk-based oversight of outsourced data management models
- Comprehensive knowledge of clinical trial data lifecycle management including database design data review external data reconciliation and database lock activities
- Thorough understanding of applicable regulatory requirements including FDA EMA ICH-GCP and industry data standards such as CDISC
- Demonstrated ability to identify and proactively mitigate operational quality and data integrity risks across multiple studies and programs
- Strong strategic thinking organizational and problem-solving skills with the ability to effectively manage competing priorities in a fast-paced environment
- Excellent leadership communication and stakeholder management skills with the ability to engage and influence audiences at all levels of the organization
- Proven ability to build alignment drive decisions and influence outcomes without direct authority across cross-functional teams and external partners
- Experience leading process improvement technology adoption and operational excellence initiatives to enhance quality scalability and efficiency
- Excellent communication and interpersonal skills with the ability to collaborate effectively with internal and external stakeholders
- Strong analytical and problem-solving abilities with a strategic mindset
- This position requires periodic/regular travel including up to 10% of work time which may include overnight travel
Physical Demands and Work Environment
Physical Demands:
- Constant or continuous use of a computer keyboard monitor and mouse to perform a variety of tasks
- Constant or frequent sitting standing or walking
- May lift and/or move objects of various weights
Work Environment:
- Remote: Home office; expected to travel to and work from the Companys headquarters in San Diego from time to time
- San Diego-based: On-site requirement (Monday through Thursday)
- Noise level in the work environment is usually moderate
- Fast-paced time sensitive environment with frequently changing priorities
- Handle multiple projects simultaneously
Reasonable accommodations may be provided to enable qualified individuals with disabilities to perform the essential functions of the position.
Salary Range
The salary range for this position is $225000 to $236000 per year. The final pay offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and years of experience within the job and the industry education and skills and certifications.
Benefits
Provided they meet all eligibility requirements under the applicable plan documents employees (and their eligible dependents) will be eligible to enroll in group healthcare plans that offer medical dental vision and basic life and AD&D insurance. Additional benefit programs include short-term and long-term disability insurance flexible spending accounts health savings accounts and voluntary insurance programs including voluntary life AD&D accident and critical illness. Employees will also be able to enroll in the Companys 401(k) addition employees will accrue 10 hours of paid vacation time every month and accrue 1 hour of paid sick leave for every 30 hours worked. Employees also enjoy 17 paid holidays each calendar year including a winter closure subject to applicable Company policies. All benefits are subject to the terms and conditions of the applicable plan documents and Company policies which may be amended from time to time.
Other Compensation
The hired candidate will be eligible to receive an annual discretionary bonus and an equity award subject to the terms of the applicable employment agreement plan documents and Company policies.
The information above is intended to provide a general description of benefits and other compensation and is not a substitute for applicable plan documents or company policies.
Applications for this position are anticipated to close on September 302026. For more information about this posting please contact.
Equal Employment Opportunity
Avenzo is committed to providing equal employment opportunities to all employees and applicants without regard to an individuals actual or perceived protected characteristic or characteristics or any combination of protected characteristics including race (including traits associated with race such as hair texture and protective hairstyles including braids locks and twists) ethnicity religion religious creed (including religious dress and grooming practices) color sex (including childbirth breast feeding and related medical conditions) gender gender identity or expression sexual orientation national origin ancestry citizenship status uniformed service member and veteran status marital status pregnancy age (40 and over) protected medical condition (including cancer and genetic conditions) genetic information disability (mental and physical) reproductive health decision-making medical leave or other types of protected leave (requesting or approved for leave under the Family and Medical Leave Act or the California Family Rights Act) the employee or their family members status as a victim of a qualifying act of violence political activity or affiliation use of cannabis off the job and away from the workplace association with an individual who has or is perceived to have a protected characteristic or characteristics or any combination of protected characteristics or any other protected status in accordance with all applicable federal state and local laws.
Notice to Search Firms/Third Party Agencies
Avenzo does not accept unsolicited resumes from recruiters employment agencies or search firms without a valid executed search agreement in place.
Required Experience:
Director
