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Director, Biotherapeutics Discovery

Biogen


Job Location:

San Francisco, CA - USA

Monthly Salary: $ 204000 - 281000
Posted: 10 August 2026 (30+ days ago)
Application Deadline: 7 November 2026
Vacancies: 1 Vacancy

Job Summary

On Site - South San Francisco.

About This Role

At Biogen we are committed to discovering developing and delivering innovative therapies for people living with serious neurological and immunological this role you will lead biologics efforts for Biotherapeutics Discovery at Biogens West Coast Hub in South San Francisco. You will drive cross-functional research and portfolio programs shape the strategy around tomorrows way of discovering biological drugs and advance discovery innovation in close partnership with colleagues across the broader Research organization including key teams in Cambridge MA.

What Youll Do

Lead and develop a high-performing team while advancing biologics technologies and platform innovation aligned with portfolio priorities

In strong partnership with the Cambridge MA team support antibody discovery engineering optimization and candidate selection strategies across discovery programs

Evaluate external innovation opportunities and help shape adoption of next-generation biologics capabilities

Contribute to molecular design strategies including multi-specifics novel formats affinity tuning epitope targeting and developability assessments

Partner across functions including protein engineering computational design pharmacology translational sciences Immunology and Neurology to initiate and shape discovery campaigns

Guide modality and candidate selection based on target biology mechanism of action and translational considerations and support early target assessments that test key biological hypotheses

Coach and mentor scientists fostering technical growth scientific excellence and strong collaboration

Build an inclusive culture of innovation accountability and continuous learning

Who You Are

You are a strategic and collaborative scientific leader with deep expertise in biologics discovery and antibody engineering. You bring strong scientific judgment thrive at the intersection of biology and molecular design and are motivated by solving complex problems in partnership with cross-functional teams. You are also a strong people leader who is passionate about developing talent enabling collaboration and building high-performing teams that deliver meaningful scientific impact.

Qualifications

Ph.D. in biochemistry immunology molecular biology or a related scientific discipline

12 years of industry experience in biologics drug discovery including leadership of antibody discovery and optimization programs

Proven success advancing molecules from discovery through candidate nomination

Deep expertise in antibody engineering molecular design and biologics discovery workflows

Experience across biologics modalities including bispecifics fusion proteins and conjugates

Demonstrated experience leading and developing scientific teams

Strong track record of cross-functional partnership including collaboration with disease biology teams

Excellent communication and leadership skills with the ability to influence scientific direction across teams and sites

Additional Qualifications

Experience in translational immunology and a strong understanding of immunology disease biology

Experience partnering with Immunology or Neurology research teams

Background in early target assessment and discovery campaign initiation

Experience identifying and sourcing external innovation through collaborations with CROs biotech companies or academic groups

Familiarity with computational design or AI/ML applications in biologics discovery


Job Level: Management


Additional Information

The base compensation range for this role is: $204000.00-$281000.00


Base salary offered is determined through an analytical approach utilizing a combination of factors including but not limited to relevant skills & experience job location and internal equity.


Regular employees are eligible to receive both short term and long-term incentives including cash bonus and equity incentive opportunities designed to reward recent achievements and recognize your future potential based on individual business unit and company performance.


In addition to compensation Biogen offers a full and highly competitive range of benefits designed to support our employees and their families physical financial emotional and social well-being; including but not limited to:

  • Medical Dental Vision & Life insurances
  • Fitness & Wellness programs including a fitness reimbursement
  • Short- and Long-Term Disability insurance
  • A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
  • Up to 12 company paid holidays 3 paid days off for Personal Significance
  • 80 hours of sick time per calendar year
  • Paid Maternity and Parental Leave benefit
  • 401(k) program participation with company matched contributions
  • Employee stock purchase plan
  • Tuition reimbursement of up to $10000 per calendar year
  • Employee Resource Groups participation

Why Biogen

We are a global team with a commitment to excellence and a pioneering spirit. As a mid-sized biotechnology company we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning growth and expanding their skills. Above all we work together to deliver life-changing medicines with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.


At Biogen we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds cultures and perspectives make us a stronger and more innovative company and we are focused on building teams where every employee feels empowered and inspired.Read onto learn more about Biogen.


All qualified applicants will receive consideration for employment without regard to sex gender identity or expression sexual orientation marital status race color national origin ancestry ethnicity religion age veteran status disability genetic information or any other basis protected by federal state or local law. Biogen is an E-Verify Employer in the United States.


Required Experience:

Director


About Company

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Founded in 1978, Biogen is a leading biotechnology company that pioneers innovative science to deliver new medicines to transform patientsÂ’ lives and to create value for shareholders and our communities. We apply deep understanding of human biology and leverage different modalities, ... View more

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