Co-op, Downstream Process Development
Woburn, MA - USA
Job Summary
ultraimpact Make a difference for those who need it most
We areseekinga motivated undergraduateor graduatestudent to join ourAAVDownstream Process Development team. The successful candidate will support laboratory anddatadrivenactivities that directly contribute to commercial manufacturing process development and clinical compatibility studies. This position offershandsonexperience in gene therapy downstream purification exposure toGMPaligneddevelopment workflows and the opportunity to learnindustryrelevantskills in chromatography buffer preparation and data analysis.
Core Lab & Ops: This role typically requires that the majority of the work be conducted on-site and thus will be subject to certain on-site safety protocols during the pandemic.
1. Process Development
- Support development activities for AAV downstream processes including buffer screening filtration studies and chromatography evaluations.
- Perform routine laboratory experiments under supervisionmaintaindetailed electronic lab notebook entries and present results in team meetings.
2. Commercial Manufacturing Support
- Conduct laboratory studies to support commercial manufacturing needs including column and resin lifetime extension studiesrequired.
- Assistwith investigations by providing experimental support data review or lab-based troubleshooting as needed.
3. ClinicalInUseCompatibility Support
- Contribute to clinicalinusecompatibility studies supporting material preparation sample handling and execution of defined protocols (as needed).
4. Laboratory Operations
- Prepare buffers and solutions according to established procedures to support ongoing experiments and team operations.
- Participate in core lab activities including inventory management equipment maintenance and general lab organization.
5. Data Entry & Trending
- Assistwith data entry and trending of manufacturing datasets.
- Support data management by compiling organizing and formatting process data
- Currentlypursuing abachelorsor masters degreein chemical engineering Bioengineering Biotechnology Biology Biochemistry or a related scientific field.
- Strong interest in bioprocessing AAV/gene therapy or downstream purification.
- Ability to perform experimental studies on multiple AAV programs.
- Ability to follow protocols carefully andmaintainattention to detail.
- Basic laboratory experience (academia or industry) preferred; chromatography or filtration exposure is a plus.
- Familiarity with Excel data entry or simple data analysis tools isadvantageous.
- Strong communicationskills willingness to learn and ateamorientedmindset.
U.S. Hourly Wage Range:
- $23.00-$30.00/hour. The estimated hourly range reflectsan anticipatedrange for this position. The actual hourly wage offered will depend on the candidates school year/level.
#LI-AJ1 #LI-Onsite
The typical annual salary range for this full-time position is listed below. This range reflects the characteristics of the job such as required skills and qualifications and is based on the office location noted in this job posting. The range may also be adjusted based on applicants geographic location.
This position is eligible for annual bonus and equity incentives. Actual individual pay is determined by demonstrated experience and internal equity alignment.
Pay Range
$1 - $1 USD
Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race color religion gender sexual orientation gender identity/expression national origin/ancestry age disability marital and veteran status and any other status or classification protected by applicable federal state and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law including individuals with disabilities disabled veterans for pregnancy childbirth and related medical conditions and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or in any part of the recruitment process you may contact Talent Acquisition by emailing us at .
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
About Company
Ultragenyx is focused on developing first-ever approved treatments for rare and ultrarare diseases and moving the rare disease community forward.