Cellular Molecular Pharmacology Scientist

Role Overview

We are seeking a highly motivated In Vivo Scientist to contribute to discovery research. This position will focus on HIV research including virus production characterization and support of HIV discovery efforts.

Key Responsibilities

• Lead the design execution optimization and characterization of HIV production workflows. As well as inventory management.
• Conduct HIV discovery research using primary human cells (PBMCs CD4 T cells) and immortalized cell lines (THP-1 Jurkat MT-4).
• Perform and analyze experiments utilizing multi-parameter flow cytometry (2 colors or more) RT-qPCR PCR ELISA and MSD multiplex assays.
• Generate and characterize stable cell lines expressing proteins of interest.
• Support in vivo studies including tissue collection and processing and perform ex vivo viral RNA isolation from tissues and/or blood samples.
• Analyze and interpret experimental data communicate findings and contribute to project strategy and execution.

Qualifications :

• Ph.D. in Biomedical Sciences Microbiology Immunology Virology or a related scientific discipline. Equivalent combination of a lesser degree and industry experience would also be acceptable.
• Demonstrated experience in HIV research and BSL-2 laboratory operations with a strong HIV publication record preferred.
• Familiarity with HIV host-pathogen interactions.
• Expertise in viral propagation concentration and characterization techniques including ultracentrifugation viral titer determination and neutralization assays.
• Hands-on experience with molecular biology techniques including CRISPR gene editing siRNA-mediated knockdown transfection site-directed mutagenesis and Western blotting.
• Experience with in vivo mouse studies including animal handling tissue harvesting and isolating viral RNA from ex vivo tissues and/or blood samples.
• Experience with ELISA.
• Proficiency with scientific data analysis and visualization software including FlowJo GraphPad Prism and SnapGene or Geneious Prime.
• Strong problem-solving skills attention to detail and the ability to work effectively in a collaborative research environment.
• Authorization to work in the United States indefinitely without restrictions or sponsorship.

Nice to have

• Willingness to learn omics techniques i.e. MSD multiplex assays Nomics Olink 10X Genomics scRNAseq.

Additional Information :

Position is Monday- Friday 8:00 am- 5:00 pm with overtime as needed.  Candidates currently living within a commutable distance of  West Point PA are encouraged to apply. 

Excellent full time benefits including comprehensive medical coverage dental and vision options.

• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

Remote Work :

No

Employment Type :

Full-time