Bioinformatics Engineer (Hybrid)

Pay Range: $95000.00 - $125000.00 / year

Salary offers are based on a wide range of factors including relevant skills training experience education and where applicable certifications obtained. Market and organizational factors are also considered. Successful candidates may be eligible to receive annual performance bonus compensation.

Benefits Information:

We are proud to offer best-in-class benefits and programs to support employees and their families in living healthy happy lives. Our pay and benefit plans have been designed to promote employee health in all respects physical financial and developmental. Depending on whether it is a part-time or full-time position some of the benefits offered may include:

Day 1 Medical supplemental health dental & vision for FT employees who work 30 hours

Best-in-class well-being programs

Annual no-cost health assessment program Blueprint for Wellness

healthyMINDS mental health program

Vacation and Health/Flex Time

6 Holidays plus 1 MyDay off

FinFit financial coaching and services

401(k) pre-tax and/or Roth IRA with company match up to 5% after 12 months of service

Employee stock purchase plan

Life and disability insurance plus buy-up option

Flexible Spending Accounts

Annual incentive plans

Matching gifts program

Education assistance through MyQuest for Education

Career advancement opportunities

and so much more!

About Haystack Oncology

Haystack Oncology now part of Quest Diagnostics is a next-generation liquid biopsy company focused on advancingtumor-informed minimal residual disease (MRD) testing. Our proprietary technology enables highly sensitive and specific detection of circulating tumor DNA (ctDNA) improving patient outcomes through earlier detection of residual disease.

As we continue to expand ourassay portfolio and bringcutting-edge diagnostics to the public we are seeking a skilledBioinformatics Scientist to join our growing team. This role will play a critical part in supportingclinical production testing clinical trials and assay R&D for Quest Diagnostics laboratories in the US and Europe.

Role Overview

As aBioinformatics Scientist you will develop and maintaincloud-based computational infrastructure for the analysis of genomic data from our proprietary MRD assays. You will work cross-functionally withlaboratory LIMS and IT teams to ensure seamless integration of bioinformatics workflows with clinical and research operations.

• Develop & maintain cloud infrastructure for scalable and efficient genomic data analysis.

• Implement and optimize Python and Nextflow bioinformatics workflows.

• Integrate bioinformatics pipelines with Laboratory Information Management Systems (LIMS) to streamline data processing.

• Ensure compliance with IT security and privacy controls aligning with Quest Diagnostics corporate policies.

• Apply software engineering best practices contributing to thescalability robustness and maintainability of bioinformatics pipelines.

• Develop and manage databases and applications forquality control (QC) and assay performance monitoring.

• Document and validate bioinformatics systems in compliance with regulatory and quality standards for clinical diagnostics

Required:

• Background in software or infrastructure engineering with experience inbioinformatics.

• Proficiency inbioinformatics pipeline workflow management particularlyNextflow (preferred) Cromwell or CWL.

• Hands-on experience developingcloud-native infrastructure (AWS preferred) forstorage batch computing and serverless applications.

• Expertise ininfrastructure as code (IaC) technologies such as Terraform or AWS CDK.

• Strong programming skills inPython JavaScript/TypeScript R or other relevant scripting languages.

• Experience withAPI development and integration particularly JSON-basedRESTful APIs.

• Deep understanding ofversion control (Git) CI/CD best practices and software development lifecycle (SDLC).

• Ability to workcross-functionally in a multi-disciplinary environment with minimal supervision.

• Strong problem-solving analytical and troubleshooting skills with the ability to diagnose and resolve technical issues.

• Excellent verbal and written communication skills in English with the ability to translate technical concepts for non-technical stakeholders.

Preferred:

• Experience in a clinical diagnostics or regulated environment (e.g. CLIA CAP IVDR FDA) with knowledge of software validation and regulatory requirements.

• Understanding ofcontrolled processes environment management and quality control systems in a clinical setting.

• Familiarity withDevOps methodologies.

Education:

• Bachelors Degree (Required)

• Masters Degree (Preferred