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Automation Senior Engineer II


Job Location:

Boston, NH - USA

Yearly Salary: USD 124000 - 186000
Posted: 29 September 2026 (17 hours ago)
Application Deadline: 27 December 2026
Vacancies: 1 Vacancy

Job Summary

Job Description

Role Summary

The Automation Engineer supports management and implementation of control systems for equipment in a GMP manufacturing facility. This role supports equipment upgrades troubleshooting lifecycle planning and compliant system operation as well as configuration for network integration and data historian management. The engineer provides day-to-day technical direction to contractors and works closely with Manufacturing Engineering Quality Validation and vendors.

Key Responsibilities

  • Support automation upgrades and modifications for data integrity and reliability improvements for manufacturing equipment.
  • Configure troubleshoot test and maintain PLCs HMIs industrial networks and related automation components.
  • Maintain OT asset inventories software versions patching records and equipment lifecycle plans.
  • Support vulnerability assessments backup and recovery change control commissioning and validation activities.
  • Integrate the equipment systems into the manufacturing network through configuration of interface technologies such as NATR devices and Kepware.
  • Configure and manage the site data historian.
  • Prepare and maintain automation documentation including configuration records SOPs work instructions and test records.
  • Coordinate assigned contractor activities and provide technical direction for automation work.
  • Escalate technical quality compliance and schedule risks to engineering leadership.

Required Qualifications

  • Bachelors degree in Engineering Automation Computer Engineering or a related technical field.
  • Minimum of 8 years of experience in industrial automation controls engineering or manufacturing automation.
  • Experience with PLC- and HMI-based control systems in a manufacturing environment.
  • Familiarity with GAMP 21 CFR Part 11 requirements validation change control and controlled documentation practices.
  • Strong troubleshooting communication and cross-functional collaboration skills.

Technical Skills Required

  • Siemens and/or Allen-Bradley PLCs and HMI applications
  • Industrial networking and control-system integration
  • Kepware drivers and connectors
  • AVEVA PI Historian
  • Automation testing commissioning and validation documentation
  • OT asset management patching and software-version control


At Vertex we embrace continuous learning and encourage employees to stay informed on advances in AI technology automation and industry trends. We seek talent who bring an external perspective demonstrate curiosity and sound judgment and thoughtfully adopt new capabilities that improve decision-making drive innovation increase efficiency and help deliver better outcomes for patients.

Pay Range:

$124000 - $186000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors including skills competencies experience and other job-related factors permitted by law.

At Vertex our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career financial family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter) educational assistance programs including student loan repayment a generous commuting subsidy matching charitable donations 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at


Required Experience:

Senior IC


About Company

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Vertex Pharmaceuticals invests in scientific innovation to create transformative medicines for people with serious diseases.

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