Senior Research engineer R&D Downstream Process Development viral vector

As a Scientist you will be working with filtration and purification of AAV/Lentivirus including harvest and clarification from Upstream material. Work will be conducted in new product development product care and market support projects with customer needs in focus.

We are looking for a Senior Research Engineer to join the Viral Vector Applications R&D section in Uppsala. The team consists of approximately 20 researchers focused on the development and optimization of downstream processes for viral vectors plasmids and nucleic acids including purification filtration and analytical workflows. The work is closely connected to product development translating process understanding into solutions that meet customer needs.

We are now seeking a new colleague who will work with downstream process development activities for viral vector manufacturing. The role focuses on developing optimizing and scaling purification processes with particular emphasis on filtration and chromatography operations. The successful candidate will apply process understanding to improve productivity robustness scalability and manufacturability while supporting the development of next-generation Cytiva technologies.

What Youll Do:

As a Senior Research Engineer you will focus on the development optimization and implementation of filtration and purification processes for AAV and lentiviral vectors including harvest and clarification of upstream material. Your work will span new product development product care and market support projects always with a strong customer and process performance focus.

Your responsibilities will include:

• Driving process development activities within filtration and downstream purification including experimental design method development and method verification to ensure robust and scalable processes.
• Applying a holistic understanding of the end-to-end workflow (Upstream to Downstream including analytics) to design efficient integrated process solutions and provide technically sound recommendations aligned with customer needs and regulatory requirements.
• Independently planning executing and analyzing experiments in a structured and data-driven manner and effectively communicating results in project teams and customer interactions.
• Owning and maintaining process-related infrastructure by ensuring proper use calibration and upkeep of instrumentation as well as developing and updating standard operating procedures (SOPs) to support reproducibility and quality.
• Evaluating proposing and implementing new technologies and technical solutions within your area with a focus on improving process efficiency robustness and scalability.
• Contributing to scientific dissemination by preparing and delivering posters and oral presentations at conferences translating process development outcomes into clear and impactful insights.

Who you are:

• You hold a MSc and have at least 5 years of industrial experience in biopharmaceutical process development particularly within harvest and downstream processing.
• You have hands-on experience in developing and optimizing end-to-end purification processes with a strong understanding of critical process parameters scalability and process robustness. Experience with viral vectors is highly desirable.
• You enjoy working in the lab bringing structure to complex tasks and take pride in maintaining clear accurate and well-organized documentation.
• You possess strong presentation and communication skills with the ability to translate complex process data into clear insights.
• You are fluent in English (spoken and written) and having working proficiency in Swedish in seen as a plus.

It would be a plus if you also possess experience in:

• Experience working with large-scale production equipment is considered a strong advantage and demonstrates your ability to bridge process development and manufacturing.
• You thrive on working in cross-functional teams where collaboration and communication are essential to drive projects forward. You enjoy working in a dynamic environment and maintain a strong focus on delivering robust customer-oriented process solutions.

Application

We continuously assess candidates and invite them for interviews so please dont hesitate to write and send in the application. The recruitment will be completed as soon as a suitable candidate is found.

We look forward to seeing your application.

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