Senior MSAT Specialist, Materials

Job Title: Senior MSAT Specialist Materials

Career Level: D

About Singapo0re ADC Site:

Be part of history in the making. AstraZeneca is building its first biologics manufacturing campus in Singapore a groundbreaking USD 1.5 billion investment that will serve as a global hub for innovation and excellence.

This innovative facility will deliver end-to-end Antibody-Drug Conjugate (ADC) capabilities with different manufacturing units/buildings in one campus:

• Small molecule- chemical API production
• Large molecule- monoclonal antibody manufacturing
• Conjugation
• Fill-and-finish operations including sterile filling and lyophilization
• Final secondary packaging

The campus will be equipped with innovative digital and automation infrastructure enabling autonomous manufacturing powered by artificial addition it will be designed for carbon neutrality embedding sustainability into every aspect of operations and setting a new benchmark for environmentally responsible biologics manufacturing.

In Manufacturing Science and Technology Team we are looking for passionate individuals with relevant experience who thrive in dynamic environments and bring a make-it-happen attitude. Joining us means contributing to a project that will not only transform AstraZenecas global supply chain but also advance life-changing medicines for patients everywhere.

If youre ready to shape the future of biologics and be part of a once-in-a-generation project we want you on our team.

Introduction to the Role:

Are you ready to define the standards for manufacturing materials and single-use systems that safeguard patient safety and product quality In this senior role you will be the go-to expert for materials and product-contact components across biologics API and fill-finish operations shaping how we qualify manage and continuously improve the materials that touch every medicine we make.

You will lead risk-based qualification and lifecycle strategies that directly influence manufacturing robustness regulatory compliance and speed to patients. Partnering closely with the Director of Product Technical Transfer and cross-functional teams you will translate science into reliable scalable solutions that keep our operations resilient and our pipeline moving.

Accountabilities:

Material Qualification Leadership: Strategize and continuously improve material qualification lifecycle management and supplier assessment programs to ensure compliance product quality and manufacturing robustness.

Risk-Based Assessment and Qualification: Lead risk assessments technical evaluations and qualification activities for manufacturing materials product-contact components and single-use systems ensuring fit-for-use and audit-ready documentation.

E&L Strategy and Patient Safety: Drive extractables and leachables strategies material compatibility assessments and scientific justifications that uphold regulatory compliance and protect patients.

Technology and Supplier Innovation: Evaluate and implement new materials technologies and supplier solutions to improve reliability scalability and operational performance across biologics and sterile manufacturing.

Technical Escalation and Problem Solving: Serve as the primary point of technical escalation resolving complex challenges or coordinating cross-functional solutions; apply advanced knowledge of manufacturing systems equipment and regulatory guidelines to drive effective investigations and process improvements.

Process Excellence and Change Implementation: Support the implementation of changes mitigate risks and integrate innovative technologies or methodologies; align technical goals with operational and quality objectives while meeting business priorities and customer expectations.

Capability Building and Standards: Mentor MSAT material specialists establish technical standards and best practices and enable capability development across teams; advise and coach colleagues to strengthen expertise and promote consistent ways of working.

Cross-Functional Collaboration and External Engagement: Collaborate with internal regulatory groups Quality Operations Supply Chain planning and purchasing central project teams and other sites; engage external suppliers and agencies to overcome obstacles and identify opportunities for enhancement.

Communication and Leadership Visibility: Communicate technical insights recommendations and potential innovations effectively to technical and non-technical stake-holders including senior leadership; foster adoption of digital solutions and track effectiveness.

Continuous Improvement and Industry Awareness: Stay informed on industry trends and organizational developments to continuously improve technical practices and keep expertise current; engage teams to adopt digital tools and data-driven decision making.

Essential Skills/Experience:

• Degree in technical or scientific field OR Technical/Associate/Vocational diploma with equivalent experience
• Extensive experience in regulated manufacturing environments
• Deep expertise in manufacturing or packaging operations
• Proven ability to resolve complex technical issues
• Strong knowledge of GMP SHE SOPs compliance frameworks
• Experience in applying project management principles
• Understanding of manufacturing and engineering landscapes
• Ability to explain technical decisions to diverse stake-holders

Desirable Skills/Experience:

• Hold or pursue recognised professional certification
• Broad understanding of product supply chain
• Knowledge of interdependence between machinery / equipment components/ materials and process performance
• Ability to connect supply chain operations with process optimization

When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca:

Here your technical leadership will shape how molecules become medicines through disciplined execution and bold problem solving. You will work with modern digital tools advanced single-use technologies and lean practices alongside colleagues who combine curiosity with kindness ambition with humility. We bring diverse expertise together to tackle complex manufacturing challenges accelerate delivery and reduce environmental impact so that every improvement you make resonates from the factory floor to patients and their families.

Call to Action:

Ready to set the benchmark for materials technical excellence and see your decisions translate into reliable life-changing medicines - what will you build with us next

Date Posted

Closing Date

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds with as wide a range of perspectives as possible and harnessing industry-leading skills. We believe that the more inclusive we are the better our work will be. We welcome and consider applications to join our team from all qualified candidates regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment) as well as work authorization and employment eligibility verification requirements.