Research Scientist, Pain Pharmacology

Job Description

Vertex Pharmaceuticals is seeking a Pharmacology Research Scientist to join our pain pharmacology group in San Diego. We are looking for a motivated creative and innovative scientist with a deep understanding of ion channel physiology and pharmacology and expertise in pain research. This lab-based role involves designing mechanistic studies developing cellular models of neuronal function and analyzing data to guide decision-making. Preference will be given to candidates with extensive experience using cutting edge electrophysiological and imaging techniques utilizing primary cells including human cells. The successful candidate will demonstrate a strong desire to collaborate within a multidisciplinary drug discovery team.

Key Duties and Responsibilities:

• Design and execute pharmacology studies focused on ion channel modulation.
• Develop cellular models to study neuronal excitation action potential propagation and neurotransmitter release.
• Analyze interpret and communicate pharmacological data to project teams.
• Collaborate with technology teams to integrate advanced tools into workflows.
• Ensure high standards of scientific documentation and communication.

Knowledge and Skills:

• Strong understanding of ion channel pharmacology.
• Experience with assays related to neuronal signaling and excitability.
• Experience with electrophysiological and imaging techniques utilizing primary cells including human cells
• Proven ability to design execute and interpret cellular assays.
• Strong verbal and written communication skills.
• Ability to navigate and thrive in a fast-paced highly-matrixed work environment.
• Passion for innovative solutions that improve lives.

Education and Experience:

• PhD and 0-3 years of experience or
• Masters degree and 3 years of experience or
• Bachelors degree and 6 years of experience

#LI-KM1

#LI-Onsite

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this On-Site designated role you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at