Bioinformatics Scientist

Benefits We Offer:

• 100% Medical Dental & Vision Coverage for Employees
• Paid Time Off and Paid Holidays
• 401K match up to 5%
• Educational Benefits for Career Growth
• Employee Referral Bonus
• Flexible Spending Accounts:
  • Healthcare (FSA)
  • Parking Reimbursement Account (PRK)
  • Dependent Care Assistant Program (DCAP)
  • Transportation Reimbursement Account (TRN)

Axleis seeking a highly ambitious adaptable structured and detail-orientedBioinformatics Scientistto join our vibrant team at the National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) Division of Intramural Research (DIR) Research Technologies Branch (RTB) Integrated Data Sciences Section (IDSS) in Bethesda MD.

Cover Letter Required Please Answer the Following Questions and submit application at: Bioinformatics Scientist
To be considered for this position please upload a document as your Cover Letter that answers the six questions below. Applications submitted without this document will not be considered.

1. What experience do you have working with large datasets and compute clusters
2. Describe your experience building workflows/pipelines and/or using bioinformatics software and tools to analyze data.
3. What programming languages are you comfortable using for bioinformatics data analysis
4. What bioinformatics areas are you familiar with (e.g. single cell bulk genomics transcriptomics epigenetics flow spatial metagenomics etc.)
5. What life science disciplines do you have experience in (e.g. immunology infectious disease cancer research etc.)
6. Provide examples of basic machine learning/AI concepts and/or how youve applied them in bioinformatics data analysis.

Responsibilities:

• Address bioinformatics scientific computing and data analysis needs of users within the Division of Intramural Research (DIR) at NIAID and their collaborators by lending expertise in the proper statistical design of biological experiments involving high-throughput genome-scale technologies data mining and knowledge discovery techniques automated workflow development statistical and scientific experimental design consulting.
• Provide bioinformatics support to include somatic and germline variant calling and analysis single-cell and bulk gene expression analysisde novoassembly of genomes and transcriptomes comparative genomics of model and non-model organisms proteomics ChIP-seq ATAC-seq and the development of high-throughput pipelines for the analysis of the above data modalities.
• Provide programming and troubleshooting support to the Research Technologies Branch (RTB) of the National Institute of Allergy and Infectious Diseases (NIAID) and collaborating Institutes in the dissemination of research data.
• Perform computational data analysis on genomic and clinical research data.
• Work with staff on scientific programming and experimental design. Provide statistical support/analysis on research data.
• Contribute to and co-author scientific publications in leading peer-reviewed journals.
• Contribute to the development of a scalable and flexible resource to provide NGS bioinformatics structural biological and computational machine learning data support to NIAID scientists and investigators.
• It is expected that the bioinformatics scientist will need strong skills in the following:
  • NGS analysis (whole-exome whole-genome RNA-seq ChIP-Seq both long- and short-read technologies etc.)
  • Statistical modeling
  • Scripting
  • Biological interpretation

Specific Qualifications:

• Ability to obtain and maintain a Public Trust Security clearance
• Minimum Bachelors degree in related field Masters or Ph.D. preferred
• 4 years of experience in bioinformatics
• 2 years of experience developing and maintaining production bioinformatics pipelines
• Expert in two (2) of the following languages: Python R C/C sh/bash
• Experience building images using one (1) of the following: Docker Podman Singularity/Apptainer
• Expert in one (1) pipeline framework: Snakemake Nextflow CWL/WDL
• Expertise building technical and user documentation for tools pipelines and applications
• Experience building pipelines locally on-premise using available HPC infrastructure
• Experience building pipelines/applications in the Cloud with AWS/GCP/Azure is a plus
• Experience building applications using one (1) of the following frameworks is a plus: Django Flask RShiny Electron Flutter React
• Experience working in a laboratory setting is a plus but not required

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills responsibilities duties and/or assignments required. Individuals may be required to perform duties outside of their position job description or responsibilities as needed.

The diversity of Axles employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age race gender religion national origin disability marital status covered veteran status sexual orientation status with respect to public assistance and other characteristics protected under state federal or local law and to deter those who aid abet or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact:

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidates experience qualifications skills and location.

Salary Range

$120000 - $130000 USD